Dr. Rakhmonkhoja Inomkhojaev was born in the Namangan region of Uzbekistan. He graduated from the Faculty of Oriental Studies at Tashkent State University with a specialization in Afghan (Dari and Pashto) languages and literature. In 1980, he defended his thesis, "Turkic-Persian bilingualism in the literature of India and poetry of Bayramkhan," at the Institute of Oriental Studies of the Academy of Sciences of USSR, Moscow, and was awarded the degree of Candidate of Philology. In 2005, he defended a thesis, "Conditions of the development of principles and aesthetic foundations of Afghan enlightenment literature," at the Tashkent State Institute of Oriental Studies and was awarded the degree of Doctor of Philology. During the years 1970–2005 he was a specialist in Afghan languages and literature at the Institute of Oriental Studies of the Academy of Sciences of Uzbekistan, Tashkent State University, Tashkent State Institute of Oriental Studies, taught Pashto, Dari languages and modern Afghan literature; served as director of the Center for Language Training, dean of the Faculty of Oriental Philology, Vice Rector of the Graduate Studies program, and Chair of the Department of the Literature of Oriental Countries of the Tashkent State Institute of Oriental Studies. During the years 1968–1989 he spent over five and a half years as an interpreter and translator of Afghan languages on various projects for Afghanistan. He has participated in numerous international conferences and seminars and has presented papers in India (1995, 1998), Almati (1999), Tashkent (2000) and the USA, Indiana University (2006, 2008, 2009), University of Wisconsin (2006, 2008), and Georgetown University (2008). He has published more than 50 articles, monographs and textbooks.
He has developed an Elementary Textbook of Pashto for English speakers (Indiana University, 2008, 2009). He has been teaching introductory and intermediate Pashto classes at IU since 2006.